Special guests! :P

Guest star Played as
“Weird Al” Yankovic Himself
Kathie Lee Gifford Herself
Kevin Michael Richardson Security guard
Michael York Mason Fairbanks
50 Cent Himself
Adam West Himself, Batman
Aerosmith Themselves
Alan Moore Himself
Albert Brooks Hank Scorpio, Brad Goodman, Tab Spangler,Jacques,Russ Cargill
Alec Baldwin Himself, Caleb Thorn
Alex Rocco Roger Meyers, Jr.
Alex Trebek Himself
Amy Poehler Jenda
Amy Tan Herself
Andre Agassi Himself
Andrea Martin Apu’s mother
Andy Dick Himself
Andy Serkis Cleanie
Angela Bassett Michelle Obama
Anne Bancroft Dr. Zweig
Anne Hathaway Princess Penelope, Jenny
Antonio Fargas Huggy Bear
Art Spiegelman Himself
Ashley Olsen Herself
Audrey Meadows Bea Simmons
Baha Men Sing “Who Wants a Haircut?”, Themselves
Barry White Himself
Ben Stiller Garth Motherloving
Bette Midler Herself
Beverly D’Angelo Lurleen Lumpkin
Bill Saluga Ray J. Johnson
Blink-182 Themselves
Bob Costas Himself
Bob Denver Himself
Bob Hope Himself
Bob Newhart Himself
Bobcat Goldthwait Himself
Brave Combo Play the end credits
Brendan Fraser Brad
Bret Hart Himself
Brian Grazer Himself
Britney Spears Herself
Brooke Shields Herself
Bruce Baum Himself
Bruce Vilanch Himself
Burt Ward Robin
Butch Patrick Himself
Buzz Aldrin Himself
C.F. Turner Himself
Carmen Electra Herself
Charles Napier Grant Conor, Officer Krackney, Warden
Charlie Rose Himself
Chick Hearn Announcer
Chris Martin Himself
Christina Ricci Erin
Christopher Guest Nigel Tufnel
Chuck Liddell Himself
Clarence Clemons Narrator
Cloris Leachman Mrs. Glick
Colm Meaney Tom O’Flanagan
Conan O’Brien Himself
Cooper Manning Himself
Cyndi Lauper Herself
Cypress Hill Themselves
Dan Marino Himself
Dan Rather Himself
Daniel Clowes Himself
Daniel Stern Narrator
Danny DeVito Herbert Powell
Darryl Strawberry Himself
Daryl L. Coley Bleeding Gums Murphy
Dave Thomas Rex Banner, Bob Hope
David Byrne Himself
David Crosby Himself
David Duchovny Fox Mulder
David Hyde Pierce Cecil Terwilliger, Man in the crowd
David Lander Squiggy
Delroy Lindo Gabriel
Denice Kumagai Dancer, Mother
Denis Leary Himself
Dennis Franz Himself playing Homer
Dennis Rodman Himself
Dennis Weaver Buck McCoy
Diane Tanaka Hostess
Dick Cavett Himself
Dick Clark Himself
Dick Tufeld Lost in Space robot
Diedrich Bader Sheriff
Dixie Chicks Themselves
Dolly Parton Herself
Don Cheadle Brother Faith
Don Mattingly Himself
Donald Sutherland Hollis Hurlbut
Dr. Demento Himself
Drew Barrymore Sophie
Drew Carey Himself
Dudley R. Herschbach Himself
Dustin Hoffman Mr. Bergstrom
Eartha Kitt Herself
Ed Begley, Jr. Himself
Ed McMahon Himself
Eddie Izzard Queen Elizabeth II
Edward Asner Newspaper editor
Edward Norton Devon Bradley
Eli Manning Himself
Elizabeth Taylor Maggie Simpson, Herself
Ellen Page Alaska Nebraska
Elliott Gould Himself
Elton John Himself
Elvis Costello Himself
Elvis Stojko Himself
Elwood Edwards Virtual doctor
Emily Blunt Juliet
Eric Idle Declan Desmond
Ernest Borgnine Himself
Evan Marriott Himself
Fall Out Boy Play the end credits
Fantasia Barrino Clarissa Wellington
Fran Drescher Female Golem
Frances McDormand Melanie Upfoot
Frances Sternhagen Mrs. Bellamy
Frank Gehry Himself
Frank Welker Santa’s Little Helper, Additional dog voices, Various animals, Executive Vice President dog, Laddie,Badger, Dog, Werewolf Flanders, Baboons, Lion, Stampy, Gremlin, Parrot, Princess
Frankie Muniz Thelonius
Fred Willard Wally Kogen
Fyvush Finkel Himself playing Krusty
Gailard Sartain Charles “Big” Daddy
Garry Marshall Larry Kidkill
Gary Busey Himself
Gary Coleman Himself
Gary Larson Himself
Gedde Watanabe Waiter, Father, Toilet, Factory foreman
Gene Tenace Himself
George W Bush Himself
George Carlin Munchie
George Fenneman Narrator
George Harrison Himself
George Plimpton Himself
George Takei Waiter, Wink, Akira
George Wendt Norm Peterson
Gerry Cooney Himself
Gillian Anderson Dana Scully
Glen Hansard Street musician
Glenn Close Mona Simpson
Gore Vidal Himself
Green Day Themselves
Greg Berg Rory
Hank Williams, Jr. Sings “Canyonero!”
Harry Morgan Bill Gannon
Harvey Fierstein Karl
Helen Fielding Herself
Helen Hunt Renee
Henry Corden Fred Flintstone
Henry Winkler Ramrod
Huell Howser Himself
Hugh Hefner Himself
Ian McKellen Himself
Isabel Sanford Herself
Isabella Rossellini Astrid Weller
J. K. Rowling Herself
J. K. Simmons Tabloid editor, J. Jonah Jameson
Jack Black Milo
Jack Burns Edward Christian
Jack LaLanne Himself
Jack Lemmon Frank Ormand
Jack Ong Fisherman
Jack Sheldon Amendment
Jackie Mason Rabbi Krustofski
Jackson Browne Himself
James Brown Himself
James Caan Himself
James Earl Jones Removal man, Serak the Preparer, Narrator, Alternate universe Maggie
James L. Brooks Himself
James Lipton Himself
James Patterson Himself
James Taylor Himself
James Woods Himself
Jan Hooks Manjula Nahasapeemapetilon
Jane Kaczmarek Judge Constance Harm
Jane Leeves Edwina
Janeane Garofalo Herself
Jason Bateman Himself
Jasper Johns Himself
Jay Leno Himself
Jay Mohr Christopher Walken
Jay North Himself
Jeff Bezos Himself
Jeff Goldblum MacArthur Park
Jennifer Garner Herself
Jerry Lewis Professor John Frink Sr.
Jerry Springer Himself
Jim Cummings Duncan
Jim Forbes Narrator
Jim Jarmusch Himself
Jim Lau Hong Kong doctor
Jim Varney Cooter
Joan Kenley Telephone voice
Jodie Foster Maggie Simpson
Joe C. Himself
Joe Frazier Himself
Joe Mantegna Fat Tony
Joe Montana Himself
Joe Namath Himself
Joe Pantoliano Dante Calabresis
Joey Miyashima Toshiro
John C. Reilly Himself
John DiMaggio Bender
John Goodman Meathook
John Madden Himself
John Mahoney Dr. Robert Terwilliger, Sr.
John Ratzenberger Cliff Clavin
John Updike Himself
John Waters John
Johnny Carson Himself
Johnny Cash Coyote
Johnny Kassir Possum
Johnny Unitas Himself
Jon Lovitz Artie Ziff, Jay Sherman, Llewelyn Sinclair, Aristotle Amadopoulis, Professor Lombardo, Enrico Irriazio
Jon Stewart Himself
Jonah Hill Andy Hamilton
Jonathan Franzen Himself
Jonathan Taylor Thomas Luke Stetson
Jordan Nagai Charlie
José Canseco Himself
Joshua Jackson Jesse Grass
Joyce Brothers Herself
Judith Owen Herself
Julia Louis-Dreyfus Gloria
June Foray Babysitter service receptionist
Karen Maruyama Dancer, Stewardess
Kathleen Turner Stacy Lovell
Kathy Griffin Francine
Keith Olbermann Himself
Keith Richards Himself
Kelsey Grammer Sideshow Bob
Ken Griffey, Jr. Himself
Ken Levine Dan Horde
Keone Young Sumo wrestler
Kevin Michael Richardson Prisoner
Kid Rock Himself
Kiefer Sutherland Jack Bauer, Colonel
Kim Basinger Herself
Kim Cattrall Chloe Talbot, Fourth Simpson child
Kimmy Robertson Samantha Stanky
Kipp Lennon Leon Kompowsky’s singing voice
Kirk Douglas Chester J. Lampwick
Kurt Loder Himself
Lance Armstrong Himself
Larry Hagman Wallace Brady
Larry Holmes Himself
Larry King Himself
Lawrence Tierney Don Brodka
LeBron James Himself
Leeza Gibbons Herself
Lenny Kravitz Himself
Leonard Nimoy Himself
Liam Neeson Father Sean
Lily Tomlin Tammy
Linda McCartney Herself
Linda Ronstadt Herself
Lionel Richie Himself
Lisa Kudrow Alex Whitney
Lisa Leslie Herself
Little Richard Himself
Los Lobos Play end credits
Lucy Lawless Herself
Lucy Liu Madam Wu
Ludacris Himself
Luke Perry Himself
Magic Johnson Himself
Mandy Moore Tabitha Vixx
Mandy Patinkin Hugh Parkfield
Marc Wilmore Dr. Wilmore
Maria Grazia Cucinotta Francessa
Marisa Tomei Sara Sloane
Mark Cuban Himself
Mark Hamill Himself, Leavelle
Mark McGwire Himself
Markéta Irglová Eastern European woman
Martin Mull Seth
Martin Sheen The real Seymour Skinner
Marv Albert Himself
Mary Lynn Rajskub Chloe O’Brian
Mary-Kate Olsen Herself
Matt Dillon Louie
Matt Groening Himself
Matthew Perry Ultrahouse’s Matthew Perry voice
Maurice LaMarche Additional voice, Commander McBragg, Orson Welles,Billy, Horn stuffer, Fox announcer, Government official, Jock, Toucan Sam, Robert D. Eisenhower,George C. Scott, Inspector
Maya Rudolph Julia
Meg Ryan Dr. Stacy Swanson
Mel Brooks Himself
Mel Gibson Himself
Melanie Griffith Herself
Merl Reagle Himself
Meryl Streep Jessica Lovejoy
Metallica Themselves
Michael Buffer Himself
Michael Chabon Himself
Michael Imperioli Dante Calabresis Jr.
Michael Jackson Leon Kompowsky
Michael Keaton Jack Crowley
Michael McKean Jerry Rude, David St. Hubbins
Michael Moore Himself
Michelle Kwan Herself
Michelle Pfeiffer Mindy Simmons
Mick Jagger Himself
Mickey Rooney Himself
Mike Judge Hank Hill
Mike Scioscia Himself
Mitch Albom Himself
Mr. T Himself
‘N Sync Themselves
Nancy O’Dell Herself
Natalie Portman Darcy
Neil Patrick Harris Himself playing Bart Simpson
Neve Campbell Cassandra
Nichelle Nichols Herself
Nick Bakay Salem Saberhagen
NRBQ Sing “You’ll Never Stop The Simpsons”, Perform various songs, Sing “Can’t Buy Me Love”
Olympia Dukakis Zelda
Oscar De La Hoya Himself
Ozzie Smith Himself
Pamela Reed Ruth Powers
Parker Posey Becky
Pat O’Brien Himself
Pat Summerall Himself
Patrick McGoohan The Prisoner Number Six
Patrick Stewart Number One
Paul Anka Himself
Paul McCartney Himself
Paul McGuinness Himself
Paul Newman Himself
Paul Willson Florist
Paul Winfield Lucius Sweet
Paul Winfield Lucius Sweet
Penn Jillette Himself
Penny Marshall Ms. Lucille Botz
Pete Sampras Himself
Peter Bogdanovich Psychologist
Peter Frampton Himself
Peyton Manning Himself
Phil Hartman Troy McClure, Lionel Hutz, Plato, Smooth Jimmy Apollo, Cable guy, Moses, Horst, Stockbroker, Hospital chairman, Bill Clinton, Mr. Muntz, Lyle Lanley, Charlton Heston, Evan Conover, Heaven
Phil McGraw Himself
Philip Rosenthal TV Dad
Phish Themselves
Pierce Brosnan Ultrahouse’s Pierce Brosnan voice
Plácido Domingo Himself
R. Lee Ermey Colonel Leslie Hapablap
R.E.M. Themselves
Randy Bachman Himself
Randy Johnson Himself
Ray Ramano Ray Magini
Red Hot Chili Peppers Themselves
Reese Witherspoon Greta Wolfcastle
Regis Philbin Himself
Rhea Perlman Carla Tortelli
Richard Dean Anderson Himself
Richard Gere Himself
Richard Lewis Male Golem
Ricky Gervais Charles
Ringo Starr Himself
Rob Reiner Himself
Robert Englund Freddy Krueger
Robert Evans Himself
Robert Forster Lucky Jim
Robert Goulet Himself
Robert Pinsky Himself
Robert Schimmel Convict
Robert Wagner Himself
Rod Steiger Captain Tenille
Rodney Dangerfield Larry Burns
Ron Howard Himself
Ron Taylor Bleeding Gums Murphy
Ronaldo Himself
Rosey Grier Himself
Roy Fireston Himself
Rudy Giuliani Himself
Rupert Murdoch Himself
Sab Shimono Mr. Sparkle, Factory worker, Japanese fisherman,Master Sushi Chef
Sacha Baron Cohen Jakob
Sal Bando Himself
Sally Stevens Sings “Scorpio”
Sam McMurray Gulliver Dark
Sam Neill Molloy
Sara Gilbert Laura Powers
Sarah Michelle Gellar Gina Vendetti
Sarah Silverman Nikki
Scott Thompson Grady
Serena Williams Herself
Seth Rogen Lyle McCarthy
Shawn Colvin Rachel Jordan
Shohreh Aghdashloo Mina
Simon Cowell Henry
Sir Mix-a-Lot Sings “Baby Likes Fat”
Smothers Brothers Themselves
Sonic Youth Themselves
Stacy Keach Howard K. Duff VII, Howard K. Duff VIII
Stan Lee Himself
Stephen Colbert Colby Kraus
Stephen Hawking Himself
Stephen Jay Gould Himself
Stephen King Himself
Stephen Sondheim Himself
Steve Allen Electronically altered voice of Bart, Himself
Steve Buscemi Himself, Dwight David Diddlehoffer
Steve Martin Ray Patterson
Steve Sax Himself
Steven Weber Neil
Steven Wright Himself
Sting Himself
Susan Sarandon Ballet teacher, Herself
Susie Smith Herself
Suzanne Somers Herself
Ted Danson Sam Malone
Ted Nugent Himself
Teller Himself
Terry Bradshaw Himself
Terry Cashman Sings “Talkin’ Softball”
Terry Gross Herself
The B-52’s Sing “Glove Slap”
The Dapper Dans The singing voices of the Be Sharps
The Moody Blues Themselves
The Ramones Themselves
The Rolling Stones Themselves
The Smashing Pumpkins Themselves
The White Stripes Themselves
The Who Themselves
Thomas Pynchon Himself
Tim Conway Himself
Tim Robbins Jim Hope
Tito Puente Himself
Tom Arnold Himself
Tom Brady Himself
Tom Clancy Himself
Tom Hanks Himself
Tom Jones Himself
Tom Kite Himself
Tom Petty Himself
Tom Poston Capitol City Goofball
Tom Savini Himself
Tom Wolfe Himself
Tony Bennett Himself
Tony Blair Himself
Tony Hawk Himself
Topher Grace Donny
Tracey Ullman Emily Winthropp
Trevor Denman Track announcer
Troy Aikman Himself
U2 Themselves
Venus Williams Herself
Wade Boggs Himself
Warren Sapp Himself
Werner Klemperer Colonel Klink
Will Shortz Himself
Willem Dafoe The Commandant
William Daniels K.I.T.T.
William H. Macy Himself
Willie Nelson Himself
Winona Ryder Allison Taylor
Wolfgang Puck Himself
Woody Harrelson Woody Boyd
Wren T. Brown Virgil
Yael Naim Doreet
Yao Ming Himself
Yo La Tengo Play end credits
Zooey Deschanel Mary

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